Tylenol Extra Strength Pain Relief Caplets temporarily reduce fever and relieve minor aches and pains. Each 500 mg acetaminophen pain relief tablet provides strong, fast acting pain relief from headache, backache, toothache, muscle aches, minor arthritis pain, the common cold, and menstrual or premenstrual cramps. From the #1 doctor-recommended brand for pain relief and fever reduction, these extra-strength 500 mg acetaminophen caplets offer an excellent safety profile when used as directed. This powerful pain relief medicine is a great option for pain and fever relief. Indicated for adults and children aged 12 and older, this fever reducer and pain medicine delivers trusted, effective relief when used as directed. Adults and children 12 years and over, take two caplets every six hours while symptoms last. Do not take more than six extra strength acetaminophen caplets in 24-hours unless directed by a doctor.